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人8型腺病毒DNA的限制性酶切图谱。

Restriction site maps of the human adenovirus type 8 DNA.

作者信息

Takács M, Berencsi G, Lengyel A, Nász I

出版信息

Acta Virol. 1983 Jul;27(4):289-98.

PMID:6138993
Abstract

Restriction site maps of human adenovirus 8 (Ad h 8) were constructed with BamHI, HindIII, PstI, SalI and KpnI endonucleases. The genome size was found to be 22.1 to 22.3 X 10(6) Mr. Comparison of the results with the data available on h Ad subgenera A, B, C showed that the SalI enzyme revealed subgenus-specific differences in the genomes. Similar patterns of the SalI fragments in both type 8 and 10 suggest that the differences were specific for the subgenus D of h Ad.

摘要

用人腺病毒8型(Ad h 8)的BamHI、HindIII、PstI、SalI和KpnI内切核酸酶构建了限制酶切图谱。发现基因组大小为22.1至22.3×10⁶道尔顿。将结果与腺病毒A、B、C亚属的现有数据进行比较,发现SalI酶揭示了基因组中亚属特异性差异。8型和10型中SalI片段的相似模式表明,这些差异是腺病毒D亚属特有的。

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