Borriello S P, Larson H E, Welch A R, Barclay F, Stringer M F, Bartholomew B A
Lancet. 1984 Feb 11;1(8372):305-7. doi: 10.1016/s0140-6736(84)90359-3.
Free Clostridium perfringens enterotoxin was detected in the stools of 11 patients with diarrhoea. All had high faecal counts of enterotoxigenic strains of C perfringens, mostly of serotypes not commonly associated with food poisoning. 10 of these 11 patients had severe or prolonged diarrhoea which had developed after antibiotic treatment. Enterotoxigenic C perfringens appears to be one of the causes of antibiotic-associated diarrhoea.
在11名腹泻患者的粪便中检测到了游离的产气荚膜梭菌肠毒素。所有患者粪便中产气荚膜梭菌产毒株数量都很高,大多数血清型通常与食物中毒无关。这11名患者中有10名在接受抗生素治疗后出现了严重或持续性腹泻。产毒产气荚膜梭菌似乎是抗生素相关性腹泻的病因之一。