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人类精浆中的肽类和类固醇激素浓度。

Peptide and steroid hormone concentrations in human seminal plasma.

作者信息

Asch R H, Fernandez E O, Siler-Khodr T M, Pauerstein C J

出版信息

Int J Fertil. 1984;29(1):25-32.

PMID:6146580
Abstract

Concentrations of peptide (alpha fraction of human chorionic gonadotropin [alpha-hCG], beta fraction of human chorionic gonadotropin [beta-hCG], luteinizing hormone [LH], follicle-stimulating hormone [FSH], and prolactin [PRL] ) and steroid hormones (testosterone [T], dihydrotestosterone [DHT], estrone [E1], estradiol [E2] and delta 4-androstenedione [A] ) were measured in the seminal plasma of 193 men. They were divided into three groups: group 1--patients attending an infertility clinic; group 2--normal volunteers of proven fertility; and group 3--men vasectomized at least 1 year prior to the study. Correlations among concentrations of hormones in seminal plasma and characteristics of the spermogram were studied. Seminal concentrations of alpha-hCG, beta-hCG, LH, T, and DHT were significantly higher in subjects with sperm in their ejaculate than in vasectomized men. No differences were observed among the groups in seminal concentrations of FSH, PRL, A, E1, and E2. Concentrations of beta-hCG and LH were highly correlated with the numbers and motility of sperm in the ejaculates. Testosterone concentrations were significantly correlated with motility of sperm.

摘要

在193名男性的精浆中测量了肽类激素(人绒毛膜促性腺激素α亚基[α-hCG]、人绒毛膜促性腺激素β亚基[β-hCG]、促黄体生成素[LH]、促卵泡生成素[FSH]和催乳素[PRL])和类固醇激素(睾酮[T]、双氢睾酮[DHT]、雌酮[E1]、雌二醇[E2]和Δ4-雄烯二酮[A])的浓度。他们被分为三组:第1组——不育门诊患者;第2组——已证实有生育能力的正常志愿者;第3组——在研究前至少1年已接受输精管切除术的男性。研究了精浆中激素浓度与精子图谱特征之间的相关性。射精中有精子的受试者精浆中α-hCG、β-hCG、LH、T和DHT的浓度显著高于输精管切除术后的男性。FSH、PRL、A、E1和E2的精浆浓度在各组之间未观察到差异。β-hCG和LH的浓度与射精中精子的数量和活力高度相关。睾酮浓度与精子活力显著相关。

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Peptide and steroid hormone concentrations in human seminal plasma.人类精浆中的肽类和类固醇激素浓度。
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