原发性肝癌患者的血清维生素B12和叶酸水平、维生素B12和叶酸结合蛋白
Serum vitamin B12 and folate levels, vitamin B12 and folic acid binding proteins in patients with primary carcinoma of the liver.
作者信息
Areekul S, Hitanant S, Panatampon P, Chantachum Y
出版信息
Southeast Asian J Trop Med Public Health. 1977 Dec;8(4):519-24.
Serum vitamin B12, folic acid, vitamin B12 and folic acid binding protein concentration were determined in 31 patients with primary carcinoma of the liver. Serum vitamin B12 level was found to be higher in 16 of 31 (52%) patients with carcinoma of the liver and the mean value was also significantly higher than that of the control group. There was no significant difference between the mean values of serum UBBC of these 2 groups. TCI and TCIII increased while TCII decreased considerably in the patient group. Serum folate level in patients with primary carcinoma of the liver was significantly lower than that of the control group. About 39% of these patients had serum folate level lower than the lowest value of the control group. Serum FABP in the former group was also significantly higher than that of the latter group.
对31例原发性肝癌患者测定了血清维生素B12、叶酸、维生素B12与叶酸结合蛋白浓度。发现31例肝癌患者中有16例（52%）血清维生素B12水平较高，其平均值也显著高于对照组。这两组的血清未结合维生素B12平均值无显著差异。患者组中总钴胺素I（TCI）和总钴胺素III（TCIII）升高，而总钴胺素II（TCII）显著降低。原发性肝癌患者的血清叶酸水平显著低于对照组。这些患者中约39%的血清叶酸水平低于对照组的最低值。前一组的血清叶酸结合蛋白（FABP）也显著高于后一组。
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