针对异源II型胶原蛋白进行免疫接种会在小鼠中诱发关节炎。
Immunisation against heterologous type II collagen induces arthritis in mice.
作者信息
Courtenay J S, Dallman M J, Dayan A D, Martin A, Mosedale B
出版信息
Nature. 1980 Feb 14;283(5748):666-8. doi: 10.1038/283666a0.
DOI:10.1038/283666a0
PMID:6153460
Abstract
The induction of polyarthritis in rats by intradermal immunisation with homologous or heterologous type II collagen incomplete or incomplete Freund's adjuvant was reported recently by Trentham et al. We have now produced a similar disease in certain strains of mice.
摘要
最近，特伦瑟姆等人报道了通过用同源或异源II型胶原蛋白与不完全或完全弗氏佐剂进行皮内免疫在大鼠中诱发多关节炎。我们现在已经在某些品系的小鼠中产生了类似的疾病。
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