结肠癌。癌症特异性长期生存情况。由一位外科医生治疗的615例患者系列研究。
Carcinoma of the colon. Cancer specific long-term survival. A series of 615 patients treated by one surgeon.
作者信息
Pihl E, Hughes E S, McDermott F T, Milne B J, Korner J M, Price A B
出版信息
Ann Surg. 1980 Jul;192(1):114-7. doi: 10.1097/00000658-198007000-00020.
The cancer specific survival in 615 patients undergoing resection for carcinoma of the colon is presented. The patients were operated on and managed by one surgeon between 1950--1977. Computer analysis has been made of the prospectively collected data. Results are presented as median survival in months and as percentage survivors at 5, 10, 15 and 20 years. Curative resection gave a cancer specific survival at the seventy-fifth percentile of 66 months, corresponding to 76% survival at five years and 67% at 20 years. Age and sex were not significant prognostic factors. Dukes' Stages A, B and C had five-year survivals of 88%, 78% and 60% respectively, after curative resection. The median survival after palliative resection was 14 months. Site of the primary tumor within the colon was of significant prognostic importance only when the poor survival in tumors of the transverse colon was compared with the favorable survival in those of the splenic flexure, ascending, descending and sigmoid colon.
本文呈现了615例接受结肠癌切除术患者的癌症特异性生存率。这些患者在1950年至1977年间由同一位外科医生进行手术及管理。对前瞻性收集的数据进行了计算机分析。结果以月中位数生存率以及5年、10年、15年和20年的生存百分比表示。根治性切除术后，癌症特异性生存率在第75百分位数为66个月，对应5年生存率为76%，20年生存率为67%。年龄和性别不是显著的预后因素。根治性切除术后，Dukes分期A、B和C的5年生存率分别为88%、78%和60%。姑息性切除术后的中位生存期为14个月。仅当将横结肠癌较差的生存率与脾曲、升结肠、降结肠和乙状结肠癌较好的生存率进行比较时，结肠内原发肿瘤的部位才具有显著的预后意义。
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