Battifora H, Sun T T, Bahu R M, Rao S
Hum Pathol. 1980 Nov;11(6):635-41. doi: 10.1016/s0046-8177(80)80074-8.
Indirect immunofluorescence staining in two thymomas, one case of thymic hyperplasia, 10 malignant lymphomas and three seminomas was done with an antibody prepared against keratins from human epidermis. Staining was observed only in the epithelial cells of the thymomas and thymic hyperplasia and correlated well with electron microscopic studies. Immunofluorescence staining of thymic tumors with antikeratin antibody provides a simple, specific, and sensitive method for distinguishing thymoma from lymphoma and seminoma. The method may also prove to be useful in other instances in the distinction between epithelial and nonepithelial tumors.
采用针对人表皮角蛋白制备的抗体，对两例胸腺瘤、一例胸腺增生、10例恶性淋巴瘤和3例精原细胞瘤进行了间接免疫荧光染色。仅在胸腺瘤和胸腺增生的上皮细胞中观察到染色，且与电子显微镜研究结果高度相关。用抗角蛋白抗体对胸腺肿瘤进行免疫荧光染色，为区分胸腺瘤与淋巴瘤及精原细胞瘤提供了一种简单、特异且灵敏的方法。该方法在区分上皮性肿瘤和非上皮性肿瘤的其他情况下可能也有用。
