Cooke A, Hutchings P, Marshall-Clarke S
Immunology. 1980 Dec;41(4):815-8.
Male and female progeny of a cross between CBA/N female and BALB/c male mice were tested for their ability to generate autoantigen-specific suppressor cells as a result of stimulation with crossreacting rat RBC. Male mice, hemizygous for the X-linked defect, were unable to generate these antigen-specific suppressor cells, whereas their female littermates behaved like the normal (CBA/Ca x BALB/c)F1 mice.
对CBA/N雌性小鼠和BALB/c雄性小鼠杂交产生的雄性和雌性后代进行测试,以检测它们在用交叉反应大鼠红细胞刺激后产生自身抗原特异性抑制细胞的能力。携带X连锁缺陷的半合子雄性小鼠无法产生这些抗原特异性抑制细胞,而它们的雌性同窝小鼠表现得与正常的(CBA/Ca×BALB/c)F1小鼠一样。