Evinger M, Maeda S, Pestka S
J Biol Chem. 1981 Mar 10;256(5):2113-4.
Recombinant human leukocyte interferon synthesized by Escherichia coli possesses antiproliferative activity in addition to antiviral activity. When the ability to inhibit multiplication of lymphoblastoid Daudi cells was examined, the growth-inhibitory capacity of recombinant leukocyte interferon was equivalent to that exhibited by crude human leukocyte interferon or by the homogeneous gamma 2 species of leukocyte interferon synthesized by human cells.
由大肠杆菌合成的重组人白细胞干扰素除具有抗病毒活性外，还具有抗增殖活性。在检测其抑制淋巴母细胞样Daudi细胞增殖的能力时，重组白细胞干扰素的生长抑制能力与粗制人白细胞干扰素或人细胞合成的白细胞干扰素γ2同型物所表现出的能力相当。
