5-氮杂胞苷对DNA（胞嘧啶-5）甲基化酶的抑制作用。含氮杂胞苷DNA的作用。 - Suppr

Suppr

超能文献

The inhibition of DNA(cytosine-5)methylases by 5-azacytidine. The effect of azacytosine-containing DNA.

作者信息

Friedman S

出版信息

Mol Pharmacol. 1981 Mar;19(2):314-20.

PMID:6164911

Abstract

摘要

相似文献

The inhibition of DNA(cytosine-5)methylases by 5-azacytidine. The effect of azacytosine-containing DNA.5-氮杂胞苷对DNA（胞嘧啶-5）甲基化酶的抑制作用。含氮杂胞苷DNA的作用。

Mol Pharmacol. 1981 Mar;19(2):314-20.

[Effect of 5-azacytidine on E. coli cells with different DNA-methylases].[5-氮杂胞苷对具有不同DNA甲基化酶的大肠杆菌细胞的影响]

Biokhimiia. 1985 May;50(5):749-54.

Long term instability and molecular mechanism of 5-azacytidine-induced DNA hypomethylation in normal and neoplastic tissues in vivo.体内正常组织和肿瘤组织中5-氮杂胞苷诱导的DNA低甲基化的长期不稳定性及分子机制

Mol Pharmacol. 1984 Nov;26(3):594-603.

[DNA methylation in T3 and T7 phages by DNA-adenine methylases of various types and methylase EcoK ocR+ by protein].

Dokl Akad Nauk SSSR. 1983 Nov-Dec;273(1):234-7.

Phosphorothioation of oligonucleotides strongly influences the inhibition of bacterial (M.HhaI) and human (Dnmt1) DNA methyltransferases.

Chembiochem. 2009 Mar 2;10(4):728-34. doi: 10.1002/cbic.200800798.

A site-specific DNA methylase from Escherichia coli K.

Indian J Biochem Biophys. 1981 Aug;18(4):295-7.

[Comparison of specific recognition sites of adenine and cytosine DNA-methylase of Yersinia Pestis EV 76 C dam and dcm by Escherichia coli methylases].[鼠疫耶尔森菌EV 76 C dam和dcm的腺嘌呤与胞嘧啶DNA甲基化酶的特异性识别位点与大肠杆菌甲基化酶的比较]

Biokhimiia. 1984 Oct;49(10):1594-7.

Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.含5,6-二氢-5-氮杂胞嘧啶的寡脱氧核糖核苷酸对DNA（胞嘧啶C5）-甲基转移酶的抑制机制

J Mol Biol. 1999 Feb 5;285(5):2021-34. doi: 10.1006/jmbi.1998.2426.

Analysis of DNA methylation processes related to the inhibition of DNA synthesis by 5-azacytidine in Streptomyces antibioticus ETH 7451.与5-氮杂胞苷抑制抗生链霉菌ETH 7451中DNA合成相关的DNA甲基化过程分析

Biol Chem. 1998 Apr-May;379(4-5):559-62.

[DNA-cytosine methylation in Escherichia coli MRE 600 cells].

Dokl Akad Nauk SSSR. 1976;230(4):976-8.

引用本文的文献

5-AzaCytidine Promotes Somatic Embryogenesis of Hybrid 'Zhongshanshan' by Regulating Redox Homeostasis.5-氮杂胞苷通过调节氧化还原稳态促进杂交种‘中山杉’的体细胞胚胎发生。

Plants (Basel). 2025 Apr 30;14(9):1354. doi: 10.3390/plants14091354.

Azacitidine induced lung injury: report and contemporary discussion on diagnosis and management.阿扎胞苷所致肺损伤：病例报告及关于诊断与管理的当代讨论

Front Oncol. 2024 Feb 9;14:1345492. doi: 10.3389/fonc.2024.1345492. eCollection 2024.

Hairpin-bisulfite sequencing of cells exposed to decitabine documents the process of DNA demethylation.对暴露于地西他滨的细胞进行发夹 - 亚硫酸氢盐测序记录了 DNA 去甲基化的过程。

Epigenetics. 2021 Nov;16(11):1251-1259. doi: 10.1080/15592294.2020.1861169. Epub 2020 Dec 28.

APOBEC Enzymes as Targets for Virus and Cancer Therapy.APOBEC 酶作为病毒和癌症治疗的靶点。

Cell Chem Biol. 2018 Jan 18;25(1):36-49. doi: 10.1016/j.chembiol.2017.10.007. Epub 2017 Nov 16.

Epigenetic Targeting of Platinum Resistant Testicular Cancer.铂耐药性睾丸癌的表观遗传学靶向治疗

Curr Cancer Drug Targets. 2016;16(9):789-795. doi: 10.2174/1568009616666151222150359.

5-azacytidine promotes microspore embryogenesis initiation by decreasing global DNA methylation, but prevents subsequent embryo development in rapeseed and barley.5-氮杂胞苷通过降低全基因组 DNA 甲基化促进小孢子胚胎发生起始，但阻止油菜和大麦随后的胚胎发育。

Front Plant Sci. 2015 Jun 25;6:472. doi: 10.3389/fpls.2015.00472. eCollection 2015.

DNA methylation and differential gene regulation in photoreceptor cell death.光感受器细胞死亡中的DNA甲基化与基因差异调控。

Cell Death Dis. 2014 Dec 4;5(12):e1558. doi: 10.1038/cddis.2014.512.

Trichostatin A and 5-azacytidine both cause an increase in global histone H4 acetylation and a decrease in global DNA and H3K9 methylation during mitosis in maize.曲古抑菌素 A 和 5-氮杂胞苷在玉米有丝分裂过程中均导致组蛋白 H4 乙酰化的整体增加和整体 DNA 和 H3K9 甲基化的减少。

BMC Plant Biol. 2010 Aug 18;10:178. doi: 10.1186/1471-2229-10-178.

5-azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia.5-氮杂胞苷在急性髓系白血病临床前模型中增强了lintuzumab（SGN-33）的抗白血病活性。

MAbs. 2010 Jul-Aug;2(4):440-8. doi: 10.4161/mabs.12203. Epub 2010 Jul 1.

A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis.一项针对原发性和原发性血小板增多症/真性红细胞增多症骨髓纤维化患者的5-氮杂胞苷II期研究。

Leukemia. 2008 May;22(5):965-70. doi: 10.1038/leu.2008.91. Epub 2008 Apr 3.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验