干扰素与阿昔洛韦对1型和2型单纯疱疹病毒的联合抗病毒作用。
Combined antiviral effect of interferon and acyclovir on herpes simplex virus types 1 and 2.
作者信息
Stanwick T L, Schinazi R F, Campbell D E, Nahmias A J
出版信息
Antimicrob Agents Chemother. 1981 Apr;19(4):672-4. doi: 10.1128/AAC.19.4.672.
Abstract
Acyclovir and human interferon displayed an additive to synergistic effect in reducing the number of herpes simplex viral plaque-forming units in Vero cells, suggesting a therapeutic potential for such combination therapy.
摘要
阿昔洛韦和人干扰素在减少单纯疱疹病毒在非洲绿猴肾细胞中形成蚀斑单位数量方面显示出相加至协同效应，提示这种联合疗法具有治疗潜力。
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本文引用的文献
1
Interferon and cytomegalovirus in vivo and in vitro.体内和体外的干扰素与巨细胞病毒
Proc Soc Exp Biol Med. 1967 Jul;125(3):843-9. doi: 10.3181/00379727-125-32220.
2
Effect of interferon on experimental vaccinia and herpes-simplex virus infections in rabbits' eyes.干扰素对兔眼实验性牛痘病毒和单纯疱疹病毒感染的影响。
Lancet. 1960 Sep 24;2(7152):682-4. doi: 10.1016/s0140-6736(60)91751-7.
3
Characterization of herpes simplex virus strains differing in their effects on social behaviour of infected cells.对感染细胞社会行为影响不同的单纯疱疹病毒株的特性分析。
J Gen Virol. 1968 May;2(3):357-64. doi: 10.1099/0022-1317-2-3-357.
4
Combined antiviral effects of interferon, adenine, arabinoside, hypoxanthine arabinoside, and adenine arabinoside-5'-monophosphate in human fibroblast cultures.干扰素、腺嘌呤、阿糖腺苷、阿糖次黄嘌呤及阿糖腺苷-5'-单磷酸在人成纤维细胞培养物中的联合抗病毒作用
Antimicrob Agents Chemother. 1977 Feb;11(2):299-306. doi: 10.1128/AAC.11.2.299.
5
Effect of acycloguanosine treatment of acute and latent herpes simplex infections in mice.无环鸟苷治疗小鼠急性和潜伏性单纯疱疹感染的效果。
Antimicrob Agents Chemother. 1979 Apr;15(4):554-61. doi: 10.1128/AAC.15.4.554.
6
Acylovir in oral and ganglionic herpes simplex virus infections.阿昔洛韦在口腔和神经节单纯疱疹病毒感染中的应用。
J Infect Dis. 1979 Nov;140(5):802-6. doi: 10.1093/infdis/140.5.802.
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Clinical trials with exogenous interferon: summary of a meeting.外源性干扰素临床试验：会议总结
J Infect Dis. 1979 Jan;139(1):109-23. doi: 10.1093/infdis/139.1.109.
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Effect of 9-(2-hydroxyethoxymethyl)guanine on herpesvirus-induced keratitis and iritis in rabbits.9-（2-羟乙氧甲基）鸟嘌呤对兔疱疹病毒性角膜炎和虹膜炎的作用
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