Murillo M L, Campos M S, Mataix F J, Varela G
Q J Exp Physiol. 1981 Jul;66(3):285-90. doi: 10.1113/expphysiol.1981.sp002557.
Some aspects of the digestive secretions in intact dogs (Control group) and the same dogs after resections of either 50 or 80% of the small intestine starting from the ileocaecal valve have been studied. In all of the animals the duodenal content flow, duodenal content pH, bile salts and amylase production have been determined; under fasting conditions, response to food (4% fat) and response to cholecystokinin-pancreozymin (CCK-PZ) injection (2 i.u./kg). Our results showed a decrease of pH and amylase production in resected animals, but duodenal content flow and bile salt production were not affected. The increase in duodenal content flow in response to feeding was delayed at onset in resected dogs. The pH and bile salts production were unchanged in response to food and to CCK-PZ injection in all animals, but amylase production decreased in response to food and particularly to CCK-PZ administration in resected animals.
研究了完整犬（对照组）以及从回盲瓣开始切除50%或80%小肠后的同一批犬的消化分泌物的某些方面。测定了所有动物的十二指肠内容物流、十二指肠内容物pH值、胆汁盐和淀粉酶分泌量；在禁食条件下，测定对食物（4%脂肪）的反应以及对注射胆囊收缩素-促胰酶素（CCK-PZ，2国际单位/千克）的反应。我们的结果显示，切除小肠的动物的pH值和淀粉酶分泌量降低，但十二指肠内容物流和胆汁盐分泌量未受影响。切除小肠的犬在进食时十二指肠内容物流增加的起始时间延迟。所有动物对食物和注射CCK-PZ时，pH值和胆汁盐分泌量均无变化，但切除小肠的动物对食物尤其是对注射CCK-PZ时，淀粉酶分泌量减少。
