Murillo M L, Campos M S, Mataix F J, Varela G
Rev Esp Fisiol. 1978 Dec;34(4):365-78.
Some aspects of the digestive secretions both in intact rats (control group) and in rats with resection of 50% and 80% of the small intestine starting from ileocecal valve have been studied. In every animal, the volume of duodenal content, total content of bile salts and amylasic activity have been analysed under the following experimental conditions: fasting, feeding with two diets containing 4% and 20% of fat, and intravenous injections of pancreozymin (2 UI/kg). Total content of bile salts and amylasic activity decrease in resected rats under fasting and feeding. This decrease is greater when larger portions of the intestine are removed. Rats injected with pancreozymin react in a similar way. The amylasic activity decrease in the resected rats indicates a pancreatic hypofunction caused by the resection and cannot be compensated by administration of pancreozymin. Measurements of seric cholesterol show that a 50% resection causes a decrease form normal levels and a 80% resection makes it significant.
对完整大鼠（对照组）以及从回盲瓣开始切除50%和80%小肠的大鼠的消化分泌物的某些方面进行了研究。在每只动物中，在以下实验条件下分析十二指肠内容物体积、胆汁盐总含量和淀粉酶活性：禁食、喂食含4%和20%脂肪的两种日粮以及静脉注射胰酶泌素（2 UI/kg）。在禁食和喂食情况下，切除小肠的大鼠胆汁盐总含量和淀粉酶活性降低。切除的肠段越多，这种降低越明显。注射胰酶泌素的大鼠反应相似。切除小肠的大鼠淀粉酶活性降低表明切除导致胰腺功能减退，且不能通过注射胰酶泌素来补偿。血清胆固醇测量结果显示，切除50%会导致从正常水平下降，切除80%则下降显著。
