Oepen G, Ostertag C
J Neurol. 1981;225(3):189-96. doi: 10.1007/BF00313748.
Striatal and cortical atrophy are significant features in the pathology of Huntington's chorea (HCh). A correlative study revealed that the CT findings of atrophy in HCh (8 patients) parallel the clinical and neurophysiological findings. In offspring (8 subjects) of HCh patients, however, the CT changes were insignificant although neurophysiological data were already suspicious in four of them. One patient with hereditary non-progressive chorea showed no CT changes at all. Perhaps with a more sensitive CT scanning technique minor morphological alterations may also be detected and used for a pre-clinical diagnosis.
纹状体和皮质萎缩是亨廷顿舞蹈病（HCh）病理学的显著特征。一项相关性研究显示，HCh患者（8例）的CT萎缩表现与临床及神经生理学表现相符。然而，在HCh患者的后代（8名受试者）中，尽管其中4人的神经生理学数据已显示可疑，但CT改变并不显著。1例遗传性非进行性舞蹈病患者的CT检查完全没有变化。或许采用更敏感的CT扫描技术，也能检测到轻微的形态学改变，并用于临床前诊断。
