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在确诊亨廷顿舞蹈症方面,直接CT尾状核测量法是否优于间接参数?

Is direct CT caudatometry superior to indirect parameters in confirming Huntington's disease?

作者信息

Lang C

出版信息

Neuroradiology. 1985;27(2):161-3. doi: 10.1007/BF00343789.

DOI:10.1007/BF00343789
PMID:3157882
Abstract

The largest diameter and area of the head of the caudate nucleus in the CT slice closest to the foramina of Monro were compared to other conventional parameters used in confirming Huntington's disease and contrasted with two groups of non-Huntington patients. A maximum diameter under 6.5 mm and an area under 92.5 mm2 were indicative of, but not specific for, Huntington's chorea. Without taking additional parameters into account, mainly occlusive hydrocephalus may be confused with genuine caudate atrophy. With advancing technology--especially Nuclear Magnetic Resonance imaging--it is to be hoped that direct measurement of the caudate nucleus may be easier and more reliable and emerge as a valuable adjunct to conventional measures.

摘要

将最靠近Monro孔的CT切片中尾状核头部的最大直径和面积,与用于确诊亨廷顿舞蹈症的其他传统参数进行比较,并与两组非亨廷顿病患者进行对比。最大直径小于6.5毫米且面积小于92.5平方毫米提示亨廷顿舞蹈症,但并非其特异性表现。若不考虑其他参数,主要是梗阻性脑积水可能会与真正的尾状核萎缩相混淆。随着技术的进步——尤其是核磁共振成像技术——有望更轻松、更可靠地直接测量尾状核,并成为传统测量方法的重要辅助手段。

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引用本文的文献

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J Neurol Neurosurg Psychiatry. 1996 Feb;60(2):206-8. doi: 10.1136/jnnp.60.2.206.
2
Methodological problems and clinical relevance of structural neuroimaging in dementia research.痴呆症研究中结构神经影像学的方法学问题及临床相关性
J Neural Transm Gen Sect. 1995;99(1-3):131-43. doi: 10.1007/BF01271474.
3
SPECT, CT and MRI in a Turkish family with Huntington's disease.土耳其一个患有亨廷顿舞蹈症家族的单光子发射计算机断层扫描、计算机断层扫描和磁共振成像

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