Stober T, Wussow W, Schimrigk K
Neuroradiology. 1984;26(1):25-8. doi: 10.1007/BF00328198.
In addition to the neurological findings, the functional capacity of 12 patients with Huntington's disease was evaluated quantitatively according to the Shoulson and Fahn scale [1]. This parameter was related to the following computed tomographic measurements: the greatest distance between the frontal horns (FH), the shortest distance between the heads of the caudate nuclei (bicaudate diameter, CC) and the quotient FH/CC. The ratio of the bicaudate diameter and the external diameter of the skull across the narrowest point of the heads of the caudate nuclei (CC/OTcc) was also used as well as the bicaudate diameter and the maximum internal diameter of the skull (CC/ITmax). The best correlation was found between the bicaudate diameter and functional capacity (r = -0.64, P less than 0.05). All the quotients containing the bicaudate diameter likewise showed a correlation with functional capacity, though to a less marked degree. Thus the bicaudate diameter appears to be the most specific and simple computed tomographic parameter for the differentiation of Huntington's disease from normal states or choreatic syndromes of different origin.
除了神经学检查结果外，还根据舒尔森和法恩量表[1]对12例亨廷顿舞蹈病患者的功能能力进行了定量评估。该参数与以下计算机断层扫描测量值相关：额角之间的最大距离（FH）、尾状核头部之间的最短距离（双尾状核直径，CC）以及FH/CC商。还使用了双尾状核直径与颅骨在尾状核头部最窄点处的外径之比（CC/OTcc）以及双尾状核直径与颅骨最大内径之比（CC/ITmax）。发现双尾状核直径与功能能力之间的相关性最佳（r = -0.64，P < 0.05）。所有包含双尾状核直径的商数同样显示出与功能能力的相关性，尽管程度较小。因此，双尾状核直径似乎是将亨廷顿舞蹈病与正常状态或不同起源的舞蹈症综合征区分开来的最具特异性和最简单的计算机断层扫描参数。
