Suppr超能文献

大肠杆菌16S核糖体RNA的结构组织。拓扑结构和二级结构。

Structural organization of the 16S ribosomal RNA from E. coli. Topography and secondary structure.

作者信息

Stiegler P, Carbon P, Zuker M, Ebel J P, Ehresmann C

出版信息

Nucleic Acids Res. 1981 May 11;9(9):2153-72. doi: 10.1093/nar/9.9.2153.

Abstract

Extensive studies in our laboratory using different ribonucleases resulted in valuable data on the topography of the E.coli 16S ribosomal RNA within the native 30S subunit, within partially unfolded 30S subunits, in the free state, and in association with individual ribosomal proteins. Such studies have precise details on the accessibility of certain residues and delineated highly accessible RNA regions. Furthermore, they provided evidence that the 16S rRNA is organized in its subunit into four distinct domains. A secondary structure model of the E.coli 16S rRNA has been derived from these topographical data. Additional information from comparative sequence analyses of the small ribosomal subunit RNAs from other species sequenced so far has been used.

摘要

我们实验室使用不同的核糖核酸酶进行了广泛研究,得到了关于大肠杆菌16S核糖体RNA在天然30S亚基内、部分展开的30S亚基内、游离状态下以及与单个核糖体蛋白结合时的拓扑结构的有价值数据。此类研究给出了某些残基可及性的精确细节,并描绘出了高度可及的RNA区域。此外,这些研究还证明16S rRNA在其亚基中被组织成四个不同的结构域。大肠杆菌16S rRNA的二级结构模型就是从这些拓扑数据推导出来的。我们还利用了迄今为止已测序的其他物种的小核糖体亚基RNA的比较序列分析的额外信息。

相似文献

7
Processing of the 5' end of Escherichia coli 16S ribosomal RNA.大肠杆菌16S核糖体RNA 5'端的加工
Proc Natl Acad Sci U S A. 1978 Aug;75(8):3598-602. doi: 10.1073/pnas.75.8.3598.

引用本文的文献

7
Lead-catalysed specific cleavage of ribosomal RNAs.铅催化的核糖体RNA特异性切割
Nucleic Acids Res. 1997 May 1;25(9):1817-24. doi: 10.1093/nar/25.9.1817.
8
The primary and secondary structure of yeast 26S rRNA.酵母26S核糖体RNA的一级和二级结构。
Nucleic Acids Res. 1981 Dec 21;9(24):6935-52. doi: 10.1093/nar/9.24.6935.
10
Adenine-guanine base pairing ribosomal RNA.腺嘌呤 - 鸟嘌呤碱基配对核糖体RNA
Nucleic Acids Res. 1982 Apr 24;10(8):2701-8. doi: 10.1093/nar/10.8.2701.

本文引用的文献

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验