Traub W, Sussman J L
Nucleic Acids Res. 1982 Apr 24;10(8):2701-8. doi: 10.1093/nar/10.8.2701.
Analyses of secondary structures proposed for ribosomal RNA's show that, of the different kinds of base pairs directly adjoining the ends of postulated double-helical regions, only A-G with A at the 5' end significantly exceeds the number expected for a random base distribution. An A(syn)-G(trans) hydrogen-bonded basepair is proposed. This could fit at the end of an undistorted double helix, but would prevent further base stacking, thus favoring a break in the double helix to produce a non-linear tertiary structure.
对核糖体RNA二级结构的分析表明,在假定的双螺旋区域末端直接相邻的不同碱基对中,只有5'端为A的A-G碱基对比随机碱基分布预期的数量显著更多。有人提出了一种A(顺式)-G(反式)氢键配对的碱基对。它可以位于未扭曲的双螺旋末端,但会阻止进一步的碱基堆积,从而有利于双螺旋的断裂以产生非线性三级结构。