Bencko V, Wagner V, Wagnerová M, Ondrejcák V
Postgraduate School of Medicine and Pharmacy, Prague, Czechoslovakia.
J Hyg Epidemiol Microbiol Immunol. 1990;34(1):9-15.
Forty-one male mercury-exposed workers were examined for the serum concentration levels of immunoglobulins (IgG, IgA, IgM), alpha-1-antitrypsin (A1AT), alpha-2-macroglobulin (A2M), ceruloplasmin (CPL) and orosomucoid (ORO). In the period preceding this investigation the mercury concentrations in workplace air ranged from 0.106 to 0.783 mg.m-3, the range of urinary mercury concentrations was from 0.029 to 0.545 mg.1(-1). All but two (IgG and A1AT) of the immune parameters tested were at the levels that were evidently higher than those found in a control group of 55 workers matched by age who lived in a relatively clean area. The percentage of individuals with no value out of the range of normal physiological limits was in the controls almost 80%, in the exposed 36.6% only. These findings confirm the literature data which show that an inhalation exposure to inorganic mercury may evidently have a stimulating effect on some serum proteins in humans.
对41名接触汞的男性工人进行了免疫球蛋白（IgG、IgA、IgM）、α-1抗胰蛋白酶（A1AT）、α-2巨球蛋白（A2M）、铜蓝蛋白（CPL）和类粘蛋白（ORO）血清浓度水平的检测。在本次调查之前的一段时间里，工作场所空气中汞浓度范围为0.106至0.783毫克/立方米，尿汞浓度范围为0.029至0.545毫克/升。除两项检测的免疫参数（IgG和A1AT）外，其他所有免疫参数水平均明显高于居住在相对清洁地区的55名年龄匹配的工人对照组。对照组中生理正常范围外无数值的个体比例近80%，而接触汞组仅为36.6%。这些发现证实了文献数据，即吸入无机汞对人体某些血清蛋白可能有明显的刺激作用。
