Attallah A M, Zoon K, Folks T, Huntington J, Yeatman T J
Infect Immun. 1981 Dec;34(3):1068-70. doi: 10.1128/iai.34.3.1068-1070.1981.
To identify the active molecule in human alpha interferon preparations, we performed several studies, using both partially purified interferon and homogeneous interferon. Our results indicated that there is little difference between the partially purified and the homogeneous interferon preparations in terms of antiviral activity, inhibition of deoxyribonucleic acid synthesis in human neoplastic cells, and enhancement of human natural killer cell activity.
为了鉴定人α干扰素制剂中的活性分子,我们使用部分纯化的干扰素和均一的干扰素进行了多项研究。我们的结果表明,部分纯化的干扰素制剂和均一的干扰素制剂在抗病毒活性、抑制人肿瘤细胞中的脱氧核糖核酸合成以及增强人自然杀伤细胞活性方面几乎没有差异。