Taira H, Broeze R J, Jayaram B M, Lengyel P, Hunkapiller M W, Hood L E
Science. 1980 Feb 1;207(4430):528-30. doi: 10.1126/science.7352261.
Mouse interferons of three size classes (A, 35,000 to 40,000 daltons; B, 26,000 to 33,000 daltons; and C, 20,000 daltons) were purified from Ehrlich ascites tumor cells infected with Newcastle disease virus. The sequences of the first 24 amino acids (No. 17 has not been identified) of interferons A and B are identical. The sequence of the first 20 amino acids of interferon C differs from that of A and B in 18 positions. There is partial homology in amino terminal sequence between mouse interferons A (or B) and a human fibroblast interferon and between mouse interferon C and a human lymphoblastoid interferon.
从感染新城疫病毒的艾氏腹水瘤细胞中纯化出三种大小类别的小鼠干扰素（A类，35,000至40,000道尔顿；B类，26,000至33,000道尔顿；C类，20,000道尔顿）。干扰素A和B的前24个氨基酸序列（第17号氨基酸未鉴定）相同。干扰素C的前20个氨基酸序列与A和B的序列在18个位置上不同。小鼠干扰素A（或B）与人成纤维细胞干扰素之间以及小鼠干扰素C与人淋巴母细胞干扰素之间在氨基末端序列上存在部分同源性。
