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双氢麦角毒碱(海得琴)对猫睡眠-觉醒周期的影响。

Effects of dihydroergotoxine (Redergine) on the sleep-wakefulness cycle in the cat.

作者信息

Susić V, Masirević G

出版信息

Gerontology. 1979;25(4):212-8. doi: 10.1159/000212342.

Abstract

Investigations with dihydroergotoxine (DHE 1.0; 3.0 and 5.0 mg/kg i.p.) indicate that DHE exerts effect on the sleep-wakefulness cycle of the cat. In doses of 3.0 and 5.0 mg/kg i.p. DHE has a suppressant effect on sleep, and in particular on REM sleep, while wakefulness was increased. With a dose of 1.0 mg/kg, wakefulness and REM sleep were decreased, while slow-wave sleep was increased.

摘要

用双氢麦角毒碱(DHE 1.0、3.0和5.0毫克/千克腹腔注射)进行的研究表明,双氢麦角毒碱对猫的睡眠-觉醒周期有影响。腹腔注射剂量为3.0和5.0毫克/千克时,双氢麦角毒碱对睡眠有抑制作用,尤其是对快速眼动睡眠,同时觉醒增加。剂量为1.0毫克/千克时,觉醒和快速眼动睡眠减少,而慢波睡眠增加。

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