Karcher D, Thormar H, Lowenthal A, Noppe M
J Neurol. 1982;227(1):29-34. doi: 10.1007/BF00313544.
Antibodies to measles virus proteins in SSPE, MS and control human sera were compared using measles virus strain Edmonston, productive SSPE strain Mantooth and non-productive SSPE strain DR. The viral antigens were subjected to transfer electrophoresis, incubated with sera and localized after a second incubation with peroxidase labeled immunoglobulins. High levels of antibodies to all measles viral proteins are present in SSPE sera and CSF and to a lesser degree in MS and control sera although the non-productive SSPE strains lack one viral protein (M protein) present in wild type measles virus strains and the productive SSPE strains.
使用麻疹病毒埃姆斯顿株、产生型亚急性硬化性全脑炎（SSPE）曼图斯株和非产生型SSPE DR株，比较了SSPE患者、多发性硬化症（MS）患者及对照人群血清中针对麻疹病毒蛋白的抗体。将病毒抗原进行转移电泳，与血清一起孵育，然后在与过氧化物酶标记的免疫球蛋白再次孵育后进行定位。尽管非产生型SSPE毒株缺乏野生型麻疹病毒株和产生型SSPE毒株中存在的一种病毒蛋白（M蛋白），但SSPE患者血清和脑脊液中存在高水平的针对所有麻疹病毒蛋白的抗体，而在MS患者及对照人群血清中该抗体水平较低。
