急性感染后及亚急性硬化性全脑炎（SSPE）患者体内针对麻疹病毒结构多肽的抗体
Antibodies to the structural polypeptides of measles virus following acute infection and in SSPE.
作者信息
Trudgett A, Bellini W J, Mingioli E S, McFarlin D E
出版信息
Clin Exp Immunol. 1980 Mar;39(3):652-6.
Abstract
A solid-phase radioimmunoassay was used to determine the specificity of IgG antibodies from normal sera, sera and CSF from patients with SSPE for the structural polypeptides of measles virus. The polypeptide specificity of antibodies from these sources were qualitatively similar; these results indicate antigenic cross-reactivity between SSPE-derived (Mantooth) and non-SSPE-derived strains of measles virus and stimulation of antibody formation by comparable antigens.
摘要
采用固相放射免疫分析法测定正常血清、亚急性硬化性全脑炎（SSPE）患者的血清及脑脊液中IgG抗体对麻疹病毒结构多肽的特异性。这些来源的抗体的多肽特异性在质量上相似；这些结果表明SSPE来源（曼托斯毒株）和非SSPE来源的麻疹病毒株之间存在抗原交叉反应，以及类似抗原对抗体形成的刺激作用。
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