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通过脂质体插入哺乳动物细胞的系统发育多样的核糖体RNA的差异分解。

Differential breakdown of phylogenetically diverse ribosomal RNA's inserted via liposomes into mammalian cells.

作者信息

Lavelle D, Ostro M J, Giacomoni D

出版信息

Science. 1982 Jul 2;217(4554):59-61. doi: 10.1126/science.6178157.

Abstract

Liposomes were used to deliver ribosomal RNA's from the different organisms into cultivated mouse plasmacytoma cells. Ribosomal RNA from Escherichia coli was degraded intracellularly within 1 hour, whereas mouse and yeast ribosomal RNA's were degraded more slowly. This indicates that cells can discriminated between different ribosomal RNA's.

摘要

脂质体被用于将来自不同生物体的核糖体RNA递送至培养的小鼠浆细胞瘤细胞中。来自大肠杆菌的核糖体RNA在1小时内于细胞内被降解,而小鼠和酵母的核糖体RNA降解得更慢。这表明细胞能够区分不同的核糖体RNA。

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