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利用被动免疫法对来自肺炎克雷伯菌和肺炎链球菌的核糖体疫苗及其核糖核酸和蛋白质组分的作用模式进行研究。

Study of the mode of action of ribosomal vaccines from Klebsiella and Streptococcus pneumoniae and their ribonucleic and protein fractions using passive immunization.

作者信息

Robert D, Ivanoff B, Fontanges R, Normier G, Pinel A M, Dussourd D'Hinterland L

出版信息

Microbiol Immunol. 1982;26(10):933-40. doi: 10.1111/j.1348-0421.1982.tb00239.x.

DOI:10.1111/j.1348-0421.1982.tb00239.x
PMID:6186896
Abstract

The vaccinating potency of ribosomal fractions of Klebsiella pneumoniae and Streptococcus pneumoniae as well as their ribosomal RNA and protein fractions has been studied with respect to their ability to induce cellular or humoral immunity. Experiments with transfer of serum or spleen cells from vaccinated animals have shown that anti-Klebsiella immunity is essentially cellular, while streptococcal immunity is exclusively humoral. Results have been discussed as a function of differential results for the various fractions under study.

摘要

已就肺炎克雷伯菌和肺炎链球菌的核糖体组分及其核糖体RNA和蛋白质组分诱导细胞免疫或体液免疫的能力,研究了它们的疫苗接种效力。对来自接种动物的血清或脾细胞进行转移实验表明,抗克雷伯菌免疫本质上是细胞免疫,而链球菌免疫则完全是体液免疫。已根据所研究的各种组分的不同结果对结果进行了讨论。

相似文献

1
Study of the mode of action of ribosomal vaccines from Klebsiella and Streptococcus pneumoniae and their ribonucleic and protein fractions using passive immunization.利用被动免疫法对来自肺炎克雷伯菌和肺炎链球菌的核糖体疫苗及其核糖核酸和蛋白质组分的作用模式进行研究。
Microbiol Immunol. 1982;26(10):933-40. doi: 10.1111/j.1348-0421.1982.tb00239.x.
2
Study of the immunogenicity of ribosomes and ribosomal RNA extracted from K. pneumoniae and S. pneumoniae.肺炎克雷伯菌和肺炎链球菌核糖体及核糖体RNA免疫原性的研究
Arzneimittelforschung. 1980;30(1a):142-72.
3
On the immunogenicity of ribosomes and ribosomal proteins isolated from Klebsiella pneumoniae and Streptococcus pneumoniae.关于从肺炎克雷伯菌和肺炎链球菌中分离出的核糖体及核糖体蛋白的免疫原性
Microbiol Immunol. 1981;25(2):183-94. doi: 10.1111/j.1348-0421.1981.tb00021.x.
4
Immunoprotective activity of capsular polysaccharide in Klebsiella pneumoniae ribosomal preparations does not involve ribonucleic acid.肺炎克雷伯菌核糖体制剂中荚膜多糖的免疫保护活性不涉及核糖核酸。
Infect Immun. 1981 Oct;34(1):126-30. doi: 10.1128/iai.34.1.126-130.1981.
5
Ribosomes as carriers for antigenic determinants of the surface of micro-organisms.核糖体作为微生物表面抗原决定簇的载体。
Dev Biol Stand. 1992;77:79-85.
6
[Antigenic similarity between polysaccharide and ribosomal vaccine extracts from Klebsiella pneumonia].[肺炎克雷伯菌多糖疫苗提取物与核糖体疫苗提取物之间的抗原相似性]
C R Seances Acad Sci III. 1981 Jan 19;292(3):281-4.
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Immunostimulative action of Streptococcus pneumoniae and Klebsiella pneumoniae subcellular fractions. I. Determination of "in vivo" toxicity and of some non-specific immunostimulative properties.肺炎链球菌和肺炎克雷伯菌亚细胞组分的免疫刺激作用。I. “体内”毒性及某些非特异性免疫刺激特性的测定。
Arch Roum Pathol Exp Microbiol. 1985 Oct-Dec;44(4):311-21.
8
Humoral immunity to Streptococcus pneumoniae induced by a pneumococcal ribosomal protein fraction.肺炎球菌核糖体蛋白组分诱导的对肺炎链球菌的体液免疫
Infect Immun. 1976 Aug;14(2):345-54. doi: 10.1128/iai.14.2.345-354.1976.
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An attempt to localize the vaccinating power of Klebsiella pneumoniae ribosomal preparations using saccharose-gradient ultracentrifugation.利用蔗糖梯度超速离心法对肺炎克雷伯菌核糖体制剂的免疫接种能力进行定位的尝试。
Microbiol Immunol. 1982;26(10):941-50. doi: 10.1111/j.1348-0421.1982.tb00240.x.
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Bacterial lysates and ribosomes as inducers of specific immune responses: a comparative study.细菌裂解物和核糖体作为特异性免疫反应的诱导剂:一项比较研究。
Scand J Immunol. 1993 Nov;38(5):496-8. doi: 10.1111/j.1365-3083.1993.tb02594.x.

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