Kole L B, Haynes S R, Jelinek W R
J Mol Biol. 1983 Apr 5;165(2):257-86. doi: 10.1016/s0022-2836(83)80257-5.
Approximately 1% of heterogeneous nuclear RNA and approximately 0.035% of cytoplasmic RNA from a cultured line of human lymphoblastoid cells is complementary to a long dispersed repetitious sequence that comprises at least 6% of human DNA. The complementary nuclear RNA is both heterogeneously and discretely sized and is present in both poly(A)-terminated and non-poly(A)-terminated molecules. The complementary cytoplasmic RNA is mainly in discretely sized molecules ranging in size from approximately 600 to 8200 bases, some of which are most abundantly represented in poly(A)-terminated molecules, whereas others are most abundantly represented in non-poly(A)-terminated molecules. Few, if any, of the complementary cytoplasmic RNAs can be found associated with polyribosomes. The dispersed repeat sequence exhibits substantial restriction enzyme fragment length polymorphisms in human DNA and is also present in mouse DNA, although some regions of the human repeat appear to be more abundantly represented in mouse DNA than are other regions.
来自人类淋巴母细胞培养系的约1%的不均一核RNA和约0.035%的细胞质RNA与一种长散在重复序列互补，该序列至少占人类DNA的6%。互补的核RNA大小不均一且离散，存在于多聚腺苷酸化（poly(A)）末端和非多聚腺苷酸化末端的分子中。互补的细胞质RNA主要存在于大小约为600至8200个碱基的离散分子中，其中一些在多聚腺苷酸化末端的分子中含量最高，而另一些在非多聚腺苷酸化末端的分子中含量最高。很少有互补的细胞质RNA（如果有的话）能与多核糖体结合。该散在重复序列在人类DNA中表现出大量的限制性酶切片段长度多态性，并且也存在于小鼠DNA中，尽管人类重复序列的某些区域在小鼠DNA中的含量似乎比其他区域更高。
