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人类Kpn I元件的重排序列。

Rearranged sequences of a human Kpn I element.

作者信息

Potter S S

出版信息

Proc Natl Acad Sci U S A. 1984 Feb;81(4):1012-6. doi: 10.1073/pnas.81.4.1012.

Abstract

The complete nucleotide sequence of a human Kpn I element inserted into alpha-satellite DNA is presented. This sequence reveals several features of interest. First, a large block of DNA normally associated with Kpn I elements has been deleted. Second, the order of the remaining sequences is permuted in a manner that cannot be accounted for by simple inversion. Third, a significant open reading frame of 675 bases is detected.

摘要

本文呈现了插入α卫星DNA中的人类Kpn I元件的完整核苷酸序列。该序列揭示了几个有趣的特征。首先,一大段通常与Kpn I元件相关的DNA已被删除。其次,其余序列的顺序以一种无法用简单倒位来解释的方式发生了重排。第三,检测到一个由675个碱基组成的重要开放阅读框。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e276/344753/331e3b5cc525/pnas00605-0037-a.jpg

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