枯草芽孢杆菌S-（2-氨基乙基）L-半胱氨酸抗性突变体的赖氨酸排泄
Lysine excretion by S-(2-aminoethyl)L-cysteine resistant mutants of Bacillus subtilis.
作者信息
Chaudhuri A, Mishra A K, Nanda G
出版信息
Acta Microbiol Pol. 1983;32(1):37-45.
PMID:6194664
Abstract
S-(2-Aminoethyl)L-cysteine (AEC) at 2 X 10(-1) mM concentration completely inhibited the growth of Bacillus subtilis. This inhibitory effect was readily reversed by 2 X 10(-2) mM L-lysine. Besides L-lysine, L-aspartic acid was only effective of all the natural amino acids tested in reversing the AEC-mediated growth inhibition. AEC resistant mutants of B. subtilis were isolated and found to excrete L-lysine in high yields.
摘要
2×10⁻¹ mM浓度的S-(2-氨基乙基)-L-半胱氨酸（AEC）完全抑制枯草芽孢杆菌的生长。2×10⁻² mM的L-赖氨酸能轻易逆转这种抑制作用。除L-赖氨酸外，在所有测试的天然氨基酸中，只有L-天冬氨酸能有效逆转AEC介导的生长抑制。分离出枯草芽孢杆菌的AEC抗性突变体，发现其能高产分泌L-赖氨酸。
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