Mariani A P
Nature. 1984;308(5955):184-6. doi: 10.1038/308184a0.
Bipolar cells are a class of retinal interneurone with dendrites in the outer plexiform layer that contact photoreceptors, and axons terminating in the inner plexiform layer where they convey the centre responses of ganglion cells. In the monkey, many of whose ganglion cells respond to stimuli selective for each of the three different cones. There are five types of cone bipolar cells: flat and invaginating midget; diffuse, flat and invaginating cone; and giant, bistratified. Although many of the monkey's ganglion cells are specific for one of the three different cone mechanisms, none of the bipolar cells are known to connect to the morphologically identified counterparts of the different spectral types of cones as in teleost retina. Here, however, I describe a bipolar cell found in Golgi preparations of the rhesus monkey retina which displays an apparently selective and patterned distribution of its dendritic contacts with cone pedicles in the outer plexiform layer. The intercone spacing of dendritic contacts and their distribution match the intercone spacing and proportion of cones thought to be blue-sensitive.
双极细胞是一类视网膜中间神经元，其树突位于外网状层，与光感受器接触，轴突终止于内网状层，在那里它们传递神经节细胞的中心反应。在猴子中，许多神经节细胞对三种不同视锥细胞各自选择性的刺激有反应。有五种类型的视锥双极细胞：扁平型和内陷型侏儒双极细胞；弥散型、扁平型和内陷型视锥双极细胞；以及巨型双分层双极细胞。尽管猴子的许多神经节细胞对三种不同视锥机制中的一种具有特异性，但与硬骨鱼视网膜不同，目前还不知道有任何双极细胞与不同光谱类型视锥细胞的形态学上已确定的对应细胞相连。然而，在这里，我描述了在恒河猴视网膜的高尔基染色标本中发现的一种双极细胞，其在外网状层与视锥细胞足突的树突接触呈现出明显的选择性和模式化分布。树突接触的视锥细胞间距及其分布与被认为对蓝光敏感的视锥细胞间距和比例相匹配。
