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羊水棕榈酸酯和皮质醇浓度比较用于预测肺成熟度。

Comparisons of the concentrations of palmitate and cortisol in amniotic fluid for the prediction of pulmonary maturity.

作者信息

Perry L A, Isherwood D M, Oakey R E

出版信息

Clin Chim Acta. 1978 Feb 1;83(1-2):171-6. doi: 10.1016/0009-8981(78)90221-8.

DOI:10.1016/0009-8981(78)90221-8
PMID:620462
Abstract

The concentrations of palmitic acid, derived from lecithin, and of cortisol in samples of amniotic fluid collected during the last trimester of human pregnancy, ranged from 28 to 420 mumol/l and from 16 to 104 nmol/l, respectively. There was a weak (r = 0.43) but significant (p less than 0.01) correlation between the concentrations of cortisol and palmitate in the samples. Measurement of the cortisol concentration in amniotic fluid provided an unreliable index of pulmonary immaturity, whether this was assessed with reference to the concentration of palmitate or from subsequent development of the respiratory distress syndrome. Measurement of cortisol in amniotic fluid cannot be recommended for this purpose.

摘要

在人类妊娠晚期采集的羊水样本中,源自卵磷脂的棕榈酸浓度和皮质醇浓度分别为28至420微摩尔/升和16至104纳摩尔/升。样本中皮质醇浓度与棕榈酸盐浓度之间存在微弱(r = 0.43)但显著(p < 0.01)的相关性。羊水皮质醇浓度的测量提供了一个不可靠的肺不成熟指标,无论这是参照棕榈酸盐浓度评估,还是根据随后呼吸窘迫综合征的发生情况评估。因此,不建议为此目的测量羊水中的皮质醇。

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