阿非科林抑制嗜盐古细菌的生长和DNA合成。
Aphidicolin inhibits growth and DNA synthesis in halophilic arachaebacteria.
作者信息
Forterre P, Elie C, Kohiyama M
出版信息
J Bacteriol. 1984 Aug;159(2):800-2. doi: 10.1128/jb.159.2.800-802.1984.
Abstract
Aphidicolin, a specific inhibitor of eucaryotic alpha DNA polymerase, inhibits the growth of halophilic arachaebacteria. In Halobacterium halobium, aphidicolin prevents cell division and DNA synthesis. These results suggest that arachaebacterial replicases are of the eucaryotic type.
摘要
阿非迪可林是真核生物α-DNA聚合酶的一种特异性抑制剂，它能抑制嗜盐古细菌的生长。在嗜盐栖热菌中，阿非迪可林可阻止细胞分裂和DNA合成。这些结果表明古细菌复制酶属于真核生物类型。
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