McKeever P E, Wichman A, Chronwall B, Thomas C, Howard R
South Med J. 1984 Aug;77(8):1027-32. doi: 10.1097/00007611-198408000-00023.
An 18-year-old woman with headaches and visual abnormalities was found upon biopsy to have an occipital gliosarcoma, which was treated with irradiation and chemotherapy for a year. Cells in the gliosarcoma tissue were positive for GFAP. At necropsy, only the sarcoma was evident at the site of original surgical removal. The sarcoma had spread widely along meningeal routes, causing the patient's death. The biologic behavior and histologic features of the sarcoma were clearly malignant. Cells cultured from the biopsy specimen maintained features in common with sarcoma.
一名18岁有头痛和视觉异常的女性经活检发现患有枕叶胶质肉瘤，接受了一年的放疗和化疗。胶质肉瘤组织中的细胞GFAP呈阳性。尸检时，仅在原手术切除部位可见肉瘤。肉瘤已沿脑膜途径广泛扩散，导致患者死亡。肉瘤的生物学行为和组织学特征明显为恶性。从活检标本培养的细胞保持了与肉瘤相同的特征。
