A rapid method for the inactivation of virus infectivity prior to assay for interferons.
作者信息
Barrett A D, Hunt N, Dimmock N J
出版信息
J Virol Methods. 1984 Jul;8(4):349-51. doi: 10.1016/0166-0934(84)90072-7.
PMID:6206084
Abstract
Virus infectivity in samples of culture medium or suspensions of animal tissue which are required for interferon assay can be rapidly and conveniently inactivated by overnight incubation with beta-propiolactone (BPL). As BPL hydrolyses spontaneously samples can be assayed with no further treatment. BPL does not affect the interfering activity of alpha, beta or gamma mouse interferons.
摘要
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