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无胆甾原体和支原体的代谢途径:概述

The metabolic pathways of Acholeplasma and Mycoplasma: an overview.

作者信息

Pollack J D, Tryon V V, Beaman K D

出版信息

Yale J Biol Med. 1983 Sep-Dec;56(5-6):709-16.

Abstract

The metabolism of the Mollicutes Acholeplasma and Mycoplasma may be characterized as restricted, for example, by virtue of the apparent absence of cytochrome pigments. Some Mollicutes have lowered ECA values during their logarithmic growth phase, which we speculate may be related to insufficient substrate phosphorylation or insufficient ATP synthesis linked to glycolysis. We found that PEP is carboxylated by preparations of A. laidlawii, but not by other Mollicutes; thus in this organism oxaloacetate from PEP may be a link to other pathways. We found phosphoribosylpyrophosphate in A. laidlawii, which suggests that ribosylation of purines and pyrimidines occurs in Mollicutes other than M. mycoides.

摘要

柔膜菌纲无胆甾原体属和支原体属的新陈代谢具有局限性,例如,明显缺乏细胞色素色素。一些柔膜菌在对数生长期的ECA值降低,我们推测这可能与底物磷酸化不足或糖酵解相关的ATP合成不足有关。我们发现莱氏无胆甾原体的制剂可使磷酸烯醇式丙酮酸羧化,但其他柔膜菌则不能;因此,在这种生物体中,由磷酸烯醇式丙酮酸生成的草酰乙酸可能是与其他途径的一个联系。我们在莱氏无胆甾原体中发现了磷酸核糖焦磷酸,这表明除蕈状支原体之外的其他柔膜菌中存在嘌呤和嘧啶的核糖基化。

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本文引用的文献

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Nutrition and metabolism of Mycoplasma mycoides var. mycoides.蕈状支原体丝状亚种的营养与代谢
Ann N Y Acad Sci. 1960 Jan 15;79:499-507. doi: 10.1111/j.1749-6632.1960.tb42716.x.
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NATURE OF BUTYRATE OXIDATION BY MYCOPLASMA HOMINIS.人型支原体对丁酸盐的氧化特性
J Bacteriol. 1965 Feb;89(2):373-7. doi: 10.1128/jb.89.2.373-377.1965.
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EVIDENCE FOR A TRICARBOXYLIC ACID CYCLE IN MYCOPLASMA HOMINIS.人型支原体中三羧酸循环的证据
J Bacteriol. 1964 Dec;88(6):1602-7. doi: 10.1128/jb.88.6.1602-1607.1964.
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DEFINED MEDIUM FOR MYCOPLASMA LAIDLAWII.莱氏无胆甾原体的限定培养基。
J Bacteriol. 1964 Jul;88(1):11-5. doi: 10.1128/jb.88.1.11-15.1964.
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GLUCOSE METABOLISM OF TWO STRAINS OF MYCOPLASMA LAIDLAWII.两株莱氏无胆甾原体的葡萄糖代谢
J Bacteriol. 1963 Oct;86(4):627-36. doi: 10.1128/jb.86.4.627-636.1963.

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