Mauzac M, Jozefonvicz J
Biomaterials. 1984 Sep;5(5):301-4. doi: 10.1016/0142-9612(84)90078-4.
Substituted dextrans bearing carboxymethyl and benzylsulphonate groups have been prepared. These materials exhibit an antithrombic activity correlated with the ratio of each substituent. The highest activity is obtained when the dextran derivative contains more than 50% of carboxylic acid groups and simultaneously about 15% of benzylsulphonate functions.
已制备出带有羧甲基和苄基磺酸酯基团的取代葡聚糖。这些材料表现出与每个取代基比例相关的抗血栓活性。当葡聚糖衍生物含有超过50%的羧酸基团且同时含有约15%的苄基磺酸酯官能团时,可获得最高活性。