Altemeier W A, Lewis S A, Schlievert P M, Bergdoll M S, Bjornson H S, Staneck J L, Crass B A
Ann Intern Med. 1982 Jun;96(6 Pt 2):978-82. doi: 10.7326/0003-4819-96-6-978.
Phage type 29 Staphylococcus aureus was identified singly or with type 52 in 64.1% of 248 coded isolates from patients with toxic shock syndrome. These phage types also have a high capability of producing pyrogenic exotoxin C and enterotoxin F. The origin and development of these toxigenic strains were explored by studying 25,220 isolates of S. aureus stored in a staphylococcal bank between 1960 and 1979. A small percentage of phage types 29, 52 were found in 1960, but their prevalence increased between 1961 and 1970, and continued at elevated levels through 1979. The toxigenic capabilities of these phage types were apparently acquired about 1971 and increased up to 1975. High levels of prevalence persisted during the following 4 years, and receded in 1980 and 1981. Other evidence during 1980 and 1981 indicates that these strains of S. aureus have become an important pathogen in surgical wounds, burns, and other infections.
在248株来自中毒性休克综合征患者的编码分离株中，29型金黄色葡萄球菌单独或与52型一起被鉴定出来，占比64.1%。这些噬菌体类型还具有高能力产生致热外毒素C和肠毒素F。通过研究1960年至1979年间保存在葡萄球菌库中的25220株金黄色葡萄球菌分离株，探索了这些产毒菌株的起源和发展。1960年发现了一小部分29型、52型噬菌体类型，但它们的流行率在1961年至1970年间有所增加，并在1979年之前一直保持在较高水平。这些噬菌体类型的产毒能力显然在1971年左右获得，并在1975年之前增加。在接下来的4年中，高流行率持续存在，并在1980年和1981年下降。1980年和1981年的其他证据表明，这些金黄色葡萄球菌菌株已成为手术伤口、烧伤和其他感染中的重要病原体。
