Nurmi T, Leinonen M, Häivä V M, Tiilikainen A, Kouvalainen K
Clin Exp Immunol. 1982 May;48(2):485-90.
The antibody response to pneumococcal vaccine was lower in adults with trisomy-21 (Down's syndrome) than in controls. Males gave lower response than females, significantly so among the 21-trisomic patients. The antibody response to different polysaccharides differed between the groups.
患有21三体综合征(唐氏综合征)的成年人对肺炎球菌疫苗的抗体反应低于对照组。男性的反应低于女性,在21三体患者中差异显著。不同组对不同多糖的抗体反应有所不同。