Potenza A D, Herte M C
J Hand Surg Am. 1982 Mar;7(2):196-9. doi: 10.1016/s0363-5023(82)80088-9.
Acellular freeze-dried canine profundus tendon allografts were placed in the knee joints of dogs and later harvested at 2, 3, and 6 weeks. All allografts remained intact, free swimming, and free of adhesions; all were covered by a layer of proliferating fibroblast-like cells that "healed" cuts made in the allografts, rounded off their previously squared-off ends, and recellularized them. The cell source for the phenomena was the synovial cell of the joint, a highly versatile, facultative fibroblast. An intrinsic capacity of flexor tendons to heal themselves cannot be critically tested by fallaciously considering synovial cavities "tissue cultures in situ," as some investigators have claimed.
将脱细胞冻干犬深肌腱同种异体移植物植入犬膝关节，随后在2周、3周和6周时取出。所有同种异体移植物均保持完整、可自由游动且无粘连；所有移植物均被一层增殖的成纤维细胞样细胞覆盖，这些细胞“修复”了同种异体移植物上的切口，使其先前呈方形的末端变圆，并使其重新细胞化。这种现象的细胞来源是关节的滑膜细胞，一种高度通用的兼性成纤维细胞。如一些研究者所声称的，将滑膜腔错误地视为“原位组织培养”，无法严格检验屈肌腱自身愈合的内在能力。
