Free S J, Metzenberg R L
Biochem Genet. 1982 Oct;20(9-10):883-9. doi: 10.1007/BF00484066.
Mutations which affect the regulation of Neurospora repressible alkaline phosphatase do so by altering the rate of de novo alkaline phosphatase synthesis. In regulatory mutants the rate of alkaline phosphatase polypeptide synthesis can vary over a 1000-fold range. Following transfer to phosphate-free medium, the wild-type cell is capable of increasing the rate of synthesis of alkaline phosphatase molecules within 30-45 min.
影响粗糙脉孢菌可阻遏碱性磷酸酶调节的突变，是通过改变从头合成碱性磷酸酶的速率来实现的。在调节突变体中，碱性磷酸酶多肽合成的速率可在1000倍的范围内变化。转移至无磷酸盐培养基后，野生型细胞能够在30 - 45分钟内提高碱性磷酸酶分子的合成速率。
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