转化细胞中的2型腺病毒信使核糖核酸：图谱位置及转运时间差异
Adenovirus type 2 mRNA in transformed cells: map positions and difference in transport time.
作者信息
Wilson M C, Sawicki S G, Salditt-Georgieff M, Darnell J E
出版信息
J Virol. 1978 Jan;25(1):97-103. doi: 10.1128/JVI.25.1.97-103.1978.
Abstract
Adenovirus type 2 rat transformed cells produced two polyadenylic acid-terminated mRNA's with approximate coordinates 1.5-4.4 and 4.4-11.0 on the physical map of the adenovirus type 2 genome. These mRNA's were also formed early during lytic infection in addition to one or more smaller mRNA's from the 4.4-11.0 region. In transformed cells, the 1.5-4.4 mRNA appeared in the cell cytoplasm without detectable lag, whereas the 4.4-11.0 mRNA required at least 20 to 30 min for the maximal rate of accumulation.
摘要
2型腺病毒转化的大鼠细胞产生了两种聚腺苷酸末端的mRNA，在2型腺病毒基因组物理图谱上的大致坐标为1.5 - 4.4和4.4 - 11.0。除了来自4.4 - 11.0区域的一种或多种较小的mRNA外，这些mRNA在裂解感染早期也会形成。在转化细胞中，1.5 - 4.4 mRNA在细胞质中出现时没有可检测到的延迟，而4.4 - 11.0 mRNA至少需要20到30分钟才能达到最大积累速率。
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