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变应性接触性皮炎中的γT细胞和对茶碱敏感的T淋巴细胞

T gamma and theophylline-sensitive T lymphocytes in allergic contact dermatitis.

作者信息

Angelini G, Vena G A, D'Ovidio R, Meneghini C L

出版信息

Arch Dermatol Res. 1982;273(3-4):241-6. doi: 10.1007/BF00409252.

DOI:10.1007/BF00409252
PMID:6219632
Abstract

Two lymphocyte subpopulations, T cells bearing a receptor for the Fc fragment of IgG (T gamma) and theophylline-sensitive T cells, were investigated in 49 patients with allergic contact dermatitis (ACD) in the acute phase and compared with a control group. Patients with ACD had markedly reduced relative T gamma and theophylline-sensitive T lymphocyte levels, compared with normals (P less than 0.0005). The patients also showed reduced absolute T gamma and theophylline-sensitive T cells with respect to the controls (P less than 0.01). To determine whether decreased levels of T gamma and theophylline-sensitive T cells were related to the activity of ACD, the same T-cell subsets were determined in 10 of 49 patients after the clearing of the contact dermatitis. Both T-cell subpopulations were found within the normal range.

摘要

对49例急性期过敏性接触性皮炎(ACD)患者的两个淋巴细胞亚群,即带有IgG Fc片段受体的T细胞(Tγ)和对茶碱敏感的T细胞进行了研究,并与一个对照组进行比较。与正常人相比,ACD患者的相对Tγ和对茶碱敏感的T淋巴细胞水平明显降低(P<0.0005)。患者的绝对Tγ和对茶碱敏感的T细胞相对于对照组也有所减少(P<0.01)。为了确定Tγ和对茶碱敏感的T细胞水平降低是否与ACD的活动有关,在49例患者中的10例接触性皮炎消退后测定了相同的T细胞亚群。发现两个T细胞亚群均在正常范围内。

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T gamma and theophylline-sensitive T lymphocytes in allergic contact dermatitis.变应性接触性皮炎中的γT细胞和对茶碱敏感的T淋巴细胞
Arch Dermatol Res. 1982;273(3-4):241-6. doi: 10.1007/BF00409252.
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本文引用的文献

1
The active E-rosette test in allergic contact dermatitis.变应性接触性皮炎中的活性E玫瑰花结试验。
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Characterization of a suppressor T-cell chronic lymphocytic leukemia with ADCC but not NK activity.具有抗体依赖性细胞介导的细胞毒性(ADCC)但无自然杀伤(NK)活性的抑制性T细胞慢性淋巴细胞白血病的特征分析
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Epidemiology of contact dermatitis.接触性皮炎的流行病学
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Depression of the T cell phenomenon of contact sensitivity by T cells from unresponsive mice.无反应小鼠的T细胞对接触敏感性T细胞现象的抑制作用。
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Tolerance and contact sensitivity to DNFB in mice. 3. Transfer of tolerance with "suppressor T cells".小鼠对二硝基氟苯的耐受性和接触敏感性。3. 用“抑制性T细胞”转移耐受性
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Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.从人血中分离单核细胞和粒细胞。通过一次离心分离单核细胞,通过离心和1g沉降相结合的方法分离粒细胞。
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Heterogeneity among human lymphocyte effector cells mediating spontaneous lymphocyte-mediated cytotoxicity.介导自发淋巴细胞介导细胞毒性的人类淋巴细胞效应细胞之间的异质性。
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Recent trends in the immunology of contact sensitivity. II.接触性敏感免疫学的近期趋势。II.
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Theophylline modulation of E-rosette formation: an indicator of T-cell maturation.茶碱对E玫瑰花结形成的调节:T细胞成熟的一个指标。
Clin Exp Immunol. 1978 Sep;33(3):503-13.