Kosugi A, Nagao M, Suwa Y, Wakabayashi K, Sugimura T
Mutat Res. 1983 Mar;116(3-4):179-84. doi: 10.1016/0165-1218(83)90058-7.
Freshly brewed blended coffee, instant coffee and instant caffeine-free coffee induced prophage lambda in lysogenic E. coli K12, strain GY5027. Because coffee prepared from green beans by the same extraction method as used for freshly brewed blended coffee had no prophage-inducing activity, this activity may be attributed to compounds produced in the roasting process. Roasting also produced compounds that were mutagenic in S. typhimurium TA100 and E. coli WP2 uvrA/pKM101.
新鲜冲泡的混合咖啡、速溶咖啡和速溶无咖啡因咖啡可诱导溶源性大肠杆菌K12菌株GY5027中的λ原噬菌体。由于采用与新鲜冲泡混合咖啡相同的提取方法从生咖啡豆制备的咖啡没有原噬菌体诱导活性,这种活性可能归因于烘焙过程中产生的化合物。烘焙还产生了在鼠伤寒沙门氏菌TA100和大肠杆菌WP2 uvrA/pKM101中具有致突变性的化合物。