衰老研究中的实验动物：要求、陷阱及对实验动物专家的一项挑战。
Animals in aging research: requirements, pitfalls and a challenge for the laboratory animal specialist.
作者信息
Solleveld H A, Hollander C F
出版信息
Vet Q. 1984 Apr;6(2):96-101. doi: 10.1080/01652176.1984.9693919.
The prime goal of aging research is to gain some insight into the basic mechanisms underlying the aging process. The long lifespan and frequent mobility of humans as well as the legal and ethical constraints on human experimentation make man unsuitable for studying the aging process. Therefore animals, particularly rodents, are used in aging research. In studying the aging process in animals, one hopes to find means for the prevention or amelioration of at least some of the disabilities of old age in man. Many intrinsic and extrinsic factors can influence the outcome of animal experiments; hence an extensive monitoring program is a prerequisite in aging research. An important role in controlling the quality of the animals is reserved for the laboratory animal specialist. Since he is faced with all aspects of laboratory animal science, aging research is a challenging area for such a specialist.
衰老研究的主要目标是深入了解衰老过程背后的基本机制。人类的长寿和频繁活动，以及人体实验所受到的法律和伦理限制，使得人类不适合用于研究衰老过程。因此，动物，特别是啮齿动物，被用于衰老研究。在研究动物的衰老过程时，人们希望找到预防或改善人类老年至少部分残疾的方法。许多内在和外在因素会影响动物实验的结果；因此，广泛的监测计划是衰老研究的先决条件。实验室动物专家在控制动物质量方面发挥着重要作用。由于他面临着实验动物科学的各个方面，衰老研究对这样的专家来说是一个具有挑战性的领域。
Zotero 插件