Wang Y G, Yan Y S, Xu J J, Du R F, Flatz S D, Kühnau W, Flatz G
Hum Genet. 1984;67(1):103-6. doi: 10.1007/BF00270566.
Lactose absorption capacity was examined in 641 apparently healthy adolescents and adults (447 males and 194 females with an average age of 22.9 years and an age range of 16-46 years) using a field version of the lactose tolerance test with breath hydrogen determination. In the total sample, 89 lactose absorbers and 552 lactose malabsorbers were identified. Lactose malabsorption was most frequent in a subgroup of Han (Chinese) from northeastern China (229 of 248 subjects, 92.3%). Among 198 Mongols from Inner Mongolia, there were 174 lactose malabsorbers (87.9%). The frequency of lactose malabsorption was lowest in a group of Kazakhs, traditional herders from the northwestern region of Xinjiang (149 of 195 subjects, 76.4%). Reported symptoms of lactose intolerance were significantly more frequent in lactose malabsorbers. The findings in northern Han are similar to the reported lactose malabsorption frequency in southern (mainly overseas) Chinese, and correspond with the absence of animal milk from traditional Chinese diets. The relatively low prevalence of lactose malabsorption among the Kazakhs suggests that lactose persistence may be frequent in herding pastoralist populations of southwest Asia.
采用呼气氢测定的乳糖耐量试验现场版，对641名表面健康的青少年和成年人（447名男性和194名女性，平均年龄22.9岁，年龄范围16 - 46岁）的乳糖吸收能力进行了检测。在总样本中，确定了89名乳糖吸收者和552名乳糖吸收不良者。乳糖吸收不良在来自中国东北的汉族（汉人）亚组中最为常见（248名受试者中有229名，占92.3%）。在198名来自内蒙古的蒙古族中，有174名乳糖吸收不良者（占87.9%）。乳糖吸收不良的发生率在一组哈萨克族中最低，哈萨克族是来自新疆西北部的传统牧民（195名受试者中有149名，占76.4%）。乳糖不耐受的报告症状在乳糖吸收不良者中明显更频繁。北方汉族的研究结果与报告的南方（主要是海外）中国人的乳糖吸收不良频率相似，并且与传统中国饮食中不含动物奶相一致。哈萨克族中乳糖吸收不良的相对低患病率表明，乳糖耐受在西南亚的游牧牧民群体中可能很常见。
