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[关于医学治疗中单独使用或与X射线联合使用的超声所产生的细胞遗传学效应的体外研究]

[In vitro study of the cytogenetic effects produced by ultrasound used in medical therapy and administered alone or in combination with X-rays].

作者信息

Decat G, Léonard A

出版信息

C R Seances Soc Biol Fil. 1984;178(2):224-9.

PMID:6235901
Abstract

Rabbit peripheral blood lymphocytes have been exposed in vitro in Go to therapeutic ultrasound (1 MHz continuous wave mode) alone or in combination with 50 rads of X-rays. The results demonstrate that ultrasound doses ranging from 0 to 960 J/cm2 delivered at intensity levels of 0.5 or 1 W/cm2 do not interfere with the cell kinetics of PHA stimulated cells and do not enhance the frequencies of sister chromatid exchanges above the control levels.

摘要

兔外周血淋巴细胞在体外处于G0期时，单独接受治疗性超声（1兆赫连续波模式）或与50拉德的X射线联合照射。结果表明，在强度为0.5或1瓦/平方厘米时，0至960焦/平方厘米的超声剂量不会干扰PHA刺激细胞的细胞动力学，也不会使姐妹染色单体交换频率高于对照水平。

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