环丙沙星及其他4-喹诺酮类药物体外对沙眼衣原体和支原体的活性。

The activity of ciprofloxacin and other 4-quinolones against Chlamydia trachomatis and Mycoplasmas in vitro.

作者信息

Ridgway G L, Mumtaz G, Gabriel F G, Oriel J D

出版信息

Eur J Clin Microbiol. 1984 Aug;3(4):344-6. doi: 10.1007/BF01977491.

DOI:10.1007/BF01977491

Abstract

Ciprofloxacin was found to be the most active of a group of 4-quinolone antibiotics tested against the SA2f strain of Chlamydia trachomatis (MBC and MIC 1.0 mg/l). Against genital isolates of Chlamydia trachomatis, ciprofloxacin was twice as active as rosoxacin. Ciprofloxacin showed similar activity to that of oxytetracycline against clinical isolates of Mycoplasma hominis and Ureaplasma urealyticum, and was 8-fold more active than rosoxacin against the latter.

摘要

在针对沙眼衣原体SA2f菌株进行测试的一组4-喹诺酮类抗生素中，环丙沙星被发现活性最强（MBC和MIC均为1.0毫克/升）。针对沙眼衣原体的生殖器分离株，环丙沙星的活性是罗索沙星的两倍。环丙沙星对人型支原体和溶脲脲原体临床分离株的活性与土霉素相似，且对后者的活性比罗索沙星高8倍。

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