Saigal S, Rosenbaum P, Stoskopf B, Sinclair J C
J Pediatr. 1984 Dec;105(6):969-76. doi: 10.1016/s0022-3476(84)80093-1.
The mortality and morbidity for all 255 live births of infants with birth weight 501 to 1000 gm and delivered to residents of a geographically defined region between 1977 and 1980 are reported. In all, 117 (46%) infants were discharged alive; there were four postdischarge deaths, and three infants were lost to follow-up. The mean birth weight and gestational age of the survivors was 850 +/- 118 gm and 27.1 +/- 2 weeks, respectively. Neurosensory handicaps were detected in 26 (24%) of 110 survivors followed for a minimum of 2 years corrected age. In addition, 29 (26%) infants had nonneurologic problems and 55 (50%) were considered apparently normal. Within 100 gm birth weight groups, survival improved significantly with increasing birth weight, but the handicap rate among survivors remained relatively constant. These figures are proposed for use in describing the current prognosis at birth for liveborn tiny infants from comparable unselected populations.
报告了1977年至1980年期间出生体重在501至1000克之间、出生于某一地理区域居民的255例活产婴儿的死亡率和发病率。总共有117名（46%）婴儿存活出院；出院后有4例死亡，3例婴儿失访。存活者的平均出生体重和胎龄分别为850±118克和27.1±2周。在110名至少随访至矫正年龄2年的存活者中，有26名（24%）检测出神经感觉障碍。此外，29名（26%）婴儿有非神经问题，55名（50%）被认为基本正常。在100克出生体重组内，随着出生体重增加，存活率显著提高，但存活者中的残疾率保持相对稳定。建议用这些数据来描述来自类似未经过选择的人群的活产极低体重婴儿出生时的当前预后情况。
