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[82例儿童糖尿病微血管病变的视网膜血管造影分析]

[Analysis of diabetic microangiopathy using retinal angiography in 82 children].

作者信息

Levy-Marchal C, Brauner R, Paredes A, Kaluzsyner M, Van Kote I, Dufier J L, Jos J, Czernichow P

出版信息

Presse Med. 1984 Dec 1;13(43):2617-20.

PMID:6239270
Abstract

Between 1979 and 1983, 116 retinal fluorescein angiographies were performed in 82 insulin-dependent diabetic children aged from 8 to 19 years. Abnormalities were observed in 7% of children with diabetes of less than 5 years duration. Retinal lesions were present in 30% of children with disease of 5-60 years duration. Most of the lesions encountered were capillary dilatations, fluorescein leakages and microaneurysms. The incidence and severity of these lesions increased with the duration of diabetes. Most of them, even of early onset, proved irreversible. It is therefore important to monitor their development by frequent angiographies (every 2 years) and to initiate an intensive treatment of diabetic children from the onset of the disease.

摘要

1979年至1983年间,对82名年龄在8至19岁的胰岛素依赖型糖尿病儿童进行了116次视网膜荧光血管造影。病程少于5年的糖尿病儿童中,7%出现异常。病程在5至60年的儿童中,30%存在视网膜病变。所遇到的大多数病变为毛细血管扩张、荧光素渗漏和微动脉瘤。这些病变的发生率和严重程度随糖尿病病程增加。其中大多数病变,即使是早期发病,也被证明是不可逆的。因此,通过频繁的血管造影(每2年一次)监测其发展,并从疾病发作起就对糖尿病儿童进行强化治疗非常重要。

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