Bjornson A B, Bjornson H S
Rev Infect Dis. 1984 Sep-Oct;6(5):704-14. doi: 10.1093/clinids/6.5.704.
A hypothesis of possible interrelationships among immunologic and hematologic sequelae of thermal injury is presented. It is postulated that there are definable pathways involving series of abnormalities with multiple interconnections among these pathways. The initiating step of each pathway should be amenable to blockade. Such blockade would theoretically circumvent the occurrence of the abnormalities or lessen their severity and thereby preserve host resistance.
本文提出了热损伤免疫和血液学后遗症之间可能存在的相互关系的假说。据推测,存在可明确的途径,这些途径涉及一系列异常,且这些途径之间存在多重相互联系。每个途径的起始步骤应可通过阻断来实现。从理论上讲,这种阻断将避免异常情况的发生或减轻其严重程度,从而维持宿主抵抗力。