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热损伤的免疫和血液学后遗症之间的理论相互关系。

Theoretical interrelationships among immunologic and hematologic sequelae of thermal injury.

作者信息

Bjornson A B, Bjornson H S

出版信息

Rev Infect Dis. 1984 Sep-Oct;6(5):704-14. doi: 10.1093/clinids/6.5.704.

DOI:10.1093/clinids/6.5.704
PMID:6239361
Abstract

A hypothesis of possible interrelationships among immunologic and hematologic sequelae of thermal injury is presented. It is postulated that there are definable pathways involving series of abnormalities with multiple interconnections among these pathways. The initiating step of each pathway should be amenable to blockade. Such blockade would theoretically circumvent the occurrence of the abnormalities or lessen their severity and thereby preserve host resistance.

摘要

本文提出了热损伤免疫和血液学后遗症之间可能存在的相互关系的假说。据推测,存在可明确的途径,这些途径涉及一系列异常,且这些途径之间存在多重相互联系。每个途径的起始步骤应可通过阻断来实现。从理论上讲,这种阻断将避免异常情况的发生或减轻其严重程度,从而维持宿主抵抗力。

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Theoretical interrelationships among immunologic and hematologic sequelae of thermal injury.热损伤的免疫和血液学后遗症之间的理论相互关系。
Rev Infect Dis. 1984 Sep-Oct;6(5):704-14. doi: 10.1093/clinids/6.5.704.
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引用本文的文献

1
Effect of thermal injury on the adherence of Candida albicans to murine splenic tissue.热损伤对白色念珠菌黏附小鼠脾脏组织的影响。
Infect Immun. 1997 Aug;65(8):3493-5. doi: 10.1128/iai.65.8.3493-3495.1997.
2
Depressed natural killer cell function in thermally injured adults: successful in vivo and in vitro immunomodulation and the role of endotoxin.热损伤成人自然杀伤细胞功能低下:体内和体外免疫调节成功及内毒素的作用
Clin Exp Immunol. 1988 Jan;71(1):120-5.
3
Pseudomonas elastase acts as a virulence factor in burned hosts by Hageman factor-dependent activation of the host kinin cascade.
铜绿假单胞菌弹性蛋白酶通过依赖于哈格曼因子激活宿主激肽级联反应,在烧伤宿主中作为一种毒力因子起作用。
Infect Immun. 1989 Nov;57(11):3345-8. doi: 10.1128/iai.57.11.3345-3348.1989.
4
Effect of proteolytic activity on virulence of Candida albicans in burned mice.蛋白水解活性对烧伤小鼠白色念珠菌毒力的影响。
Infect Immun. 1990 Jun;58(6):1527-31. doi: 10.1128/iai.58.6.1527-1531.1990.
5
Effect of an immunomodulating agent, RU 414740, on polymorphonuclear responsiveness after burn injury.免疫调节剂RU 414740对烧伤后多形核细胞反应性的影响。
Inflammation. 1991 Dec;15(6):437-45. doi: 10.1007/BF00923341.